Abstract. According to the literature consensus, nanoparticles are naturally designed or produced particulate materials, with at least one dimension nm or less. Currently, an absurd quantity of nanoparticles has been produced for the most diverse purposes. Establishing nanoparticles capable of interacting with biological nanomaterials, also called biomaterials, are materials derived from or inspired by biological systems, such as proteins, nucleic acids, and viruses. This chapter provides an overview of the synthesis, characterization, and applications of biological nanomaterials. We begin by discussing properties and synthesis,Summary. This review provides a detailed overview of the synthesis, properties and applications of nanoparticles. NPs exist in different forms. NPs are tiny materials that vary in size in nm. They can be classified into different classes based on their properties, shapes or sizes. The field of nanotechnology involves the creation and use of chemical, physical, and biological systems with structural features between simple atoms or molecules down to submicron dimensions, as well as the assimilation of The resulting nanostructures are transformed into systems larger 2, 3. The simplest definition of nanotechnology is “technology.” Nanoscience is the study of structures and materials on an ultra-small scale. A nanometer is equivalent to a billionth of a meter. The physical and chemical properties of matter change at the nanometer level. Nanotechnology has the potential to revolutionize a wide range of fields, from healthcare to manufacturing. Nanomaterials such as graphene, carbon nanotubes, Ag Au, TiO2, ZnO and CuO metal nanoparticles and bio-based nanomaterials have been used in textiles to increase their functionalities. Over the past decades, nanotechnology has contributed to the biomedical field in areas such as detection, diagnosis, and drug delivery via optoelectronic properties or enhancement of biological effects. Although they are generally considered inert carriers, a plethora of past and present evidence demonstrates that nanomaterials also release,