Literature review is an essential part of academic research. Fundamentally, the advancement of knowledge must build on existing prior work. To push the frontiers of knowledge, we need to know where the frontier is. By reviewing relevant literature, we understand the breadth and depth of the existing body of work and identify gaps to explore. Literature reviews play a vital role in scholarship because science remains, above all, a cumulative effort Brocke et al. 2009. As in any academic discipline, rigorous syntheses of knowledge are becoming essential to keep up with the exponential growth of the literature on e-health, helping practitioners and academics. The main objective of the journal is to present to the readers the need to conduct the said research. A literature review should begin with a thorough search of the literature using key keywords in relevant online databases such as Google Scholar, PubMed, etc. Once all relevant literature has been collected, it needs to be organized. A literature review is an integrated analysis of not just a summary of scientific writings and other relevant evidence directly related to your research question. That is, it represents a synthesis of evidence that provides basic information about your topic and shows an association between the evidence and your,