Abstract. Depression is one of the most common mood disorders among older adults and is associated with poor quality of life and increased morbidity, disability, and mortality. However, in older people, it often remains undetected and untreated; Background. Depression is one of the leading causes of disability worldwide and contributes significantly to the global burden of disease. Depression is one of the leading causes of disability worldwide and contributes significantly to the global burden of disease. It is also one of the most common treatment programs for depressed elderly patients suffering from cardiovascular diseases and other serious illnesses that usually last longer than normal and, Depression in the Elderly: A Call for More new therapies. Soumia Benbrika. Lucie Métivier. amp Eric Bui · 199, published online: 10. Cite this, The predictors, self-perceived social isolation and poor self-rated health were the strongest risk factors for depression among men and women of middle age and older. Instrumental difficulties. High rates of morbidity and mortality have been attributed to high levels of depression among elderly people in these facilities. Chew-Graham et al. This means that nursing intervention in elderly care homes should focus primarily on preventing or reducing levels of depression in their clients.